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Southern Cross Plant Science

George A. Davidson

georgeAnalytical Officer

t: +61 2 6622 3211
f: +61 2 6626 9126
e: george.davidson@scu.edu.au

Education:
M.B.Ch.B (University Cape Town RSA), PhD (University Cape Town, RSA), NAS I Maritime Archeology (Cardiff, UK)

Background

  • Biochemistry (Biomembranes, ion transport and gravitropism)
  • Electronics R&D (Instrumentation and detection systems)
  • Medical Director and Clinical Trial Manager (Herbal and drug delivery systems)
  • Medicinal plant Database Search engines

Specific expertise

Analytical Chemist

Other activities

Method development

Publications

  • Role of Phospholipid and Protein-Protein Associations in Activation and Stabilization of Soluble Ca2+-ATPase of Sarcoplasmic Reticulum. McIntosh, D.B. and Davidson, G.A. (1984) Biochemistry 23, 1959-1965.
  • Minimum functional unit of the Ca2+ pump of skeletal muscle Sarcoplasmic Reticulum. McIntosh, D.B., Ross, D.C. and Davidson, G.A. In Membranes and muscle, Proceedings of an International Symposium, Cape Town, March 1985 (Berman, M.C., Gevers, W. and Opie, L.H. eds.), IRL Press, Oxford, ICSU Symposium Series, Volume 6, pp 195-214.
  • Interaction of Valinomycin and Monovalent Cations with the (Ca, Mg)- ATPase of Skeletal Muscle Sarcoplasmic Reticulum. Davidson, G.A. and Berman, M.C. (1985) J. Biol. Chem., 260, 7325-7329.
  • The effect of Valinomycin on the Binding and Specificity of the Monovalent Cation Site on the (Ca, Mg)-ATPase of Skeletal Muscle Sarcoplasmic Reticulum. In Membranes and Muscle, Proceedings of an International Symposium, Cape Town, March 1985 (Berman, M.C., Gevers, W. and Opie, L.H., eds.), IRL Press, Oxford, ICSU Symposium Series, Volume 6, pp 342-343.
  • Phosphoenzyme Conformational States and Nucleotide Binding Site Hydrophobicity following thiol modification of the Ca2+-ATPase of Sarcoplasmic Reticulum. Davidson, G.A. and Berman, M.C. (1987), J. Biol. Chem. 262, 7041-7046.
  • Properties of the Non-catalytic Nucleotide Site of the Ca2+-ATPase of Sarcoplasmic Reticulum. Davidson G.A. (1986) Ph.D. Thesis, U.C.T..
  • Properties of the catalytic site following thiol modification of the Ca2+-ATPase of Sarcoplasmic Reticulum from skeletal muscle. Davidson, G.A. and Berman M.C. In Ion Pumps: Structure, Function and Regulation, eds., Karlish, S. and Stein W., Proceedings of an International Symposium, Jerusalem, Israel, August 1987..
  • Resolution of high affinity Ca2+ binding sites and Ca2+ Occlusion during single cycle Catalysis of the Sarcoplasmic Reticulum ATPase. Davidson, G.A. and Berman, M.C. In Ion Pumps: Structure, Function and Regulation, eds., Karlish, S. and Stein W., Proceedings of an International Symposium, Jerusalem, Israel, August 1987.
  • Calcium dependence during single-cycle catalysis of the Sarcoplasmic Reticulum ATPase. Davidson G.A. and Berman, M.C. (1988) J.Biol Chem 263, 11786 - 11791.
  • Kinetics of Thapsigargin - Ca2+-ATPase (Sarcoplasmic Reticulum) Interaction Reveals a Two- step Binding Mechanism and Picomolar Inhibition. George A. Davidson* and Richard J. Varhol (1995) J.Biol. Chem. 270, 11731-11734.
  • Calcium and Thapsigargin stabilize a transport channel in the Ca2+- ATPase of Sarcoplasmic Reticulum. George A. Davidson and Mervyn C. Berman, Biochem.Biophys Acta. 1996.
  • Adaptation in MscL is related to membrane thickness. Davidson G.A. and Martinac B, 2001 , J. Gen Physiol. ( to submit J Phys 2003).
  • Pressure-clamp at constant G : a method for measurement of amphipath intercalation intomembranes of mechanosensitive channels. (2002) George Davidson, Paul Chan and Boris Martinac ., Biophysics J. ( Presented at San Francisco Biophys Conference 2004.
  • Patents 2007 Nos 2004-575477P Drug Delivery Systems (Herron Pharmaceuticals).